At one point in history, ketchup was just a mixture of ingredients from fish or mushrooms. A doctor known as Dr. John Cooke Bennet was the first to add tomatoes to the ketchup recipe back in 1834. Since tomatoes are commonly known as a natural vitamin and antioxidant, Bennet claimed that his ketchup recipe can cure a variety of health issues such as diarrhea, indigestion, jaundice, and rheumatism.

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Bennet later had his sauce innovation extracted into a tomato pill. This started a wave of copycats that started to sell tomato based pills. Many of these copycats claimed that these pills can cure just about any health issue.

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Around 1840, medical professionals launched an investigation on the tomato based pills. Investigators found that many pills were just laxatives and had no trace of tomatoes. This caused the ketchup medicine industry to collapse, primarily due to violation of the false claim act.